Diploma di Maturita' Classica conseguito presso l'Istituto "Francesco Vivona"
di Roma.
1980-1981: ha frequentato il college St. Clare's Hall in Oxford, Inghilterra,
dove ha conseguito il diploma in "Business Administration" ed il "First Certificate
of English".
1982-1983: ha prestato servizio militare di leva presso "l'ottavo Gruppo Genio
Campale" dell'Areonautica militare dell'areoporto di Ciampino, Roma.
Laurea in Farmacia presso l'Universita' degli studi di Camerino, nell'anno accademico
1989/1990 con la votazione di 108/110.
TITOLI ACCADEMICI: Ph.D. in Modellistica Biomedica: Farmacocinetica e Bioingegneria,
Facolta' di Medicina e Chirurgia, Universita' di Ancona.
RICONOSCIMENTI: "Young Investigator Award" attribuito dalla Societa' internazionale
degli studi sull'"ingestive behaviour" (SSIB) nel giugno 1992.
GRANTS: "Irbesartan Research Award" grant attribuito dalla Bristol-Myers Squibb
and Sanofi, 1998.
" Biosistema s.r.l." (Biotech Company) 1999-2000.
" Biosistema s.r.l." (Biotech Company) 2000-2001.
" Biosistema s.r.l." (Biotech Company) 2001-2002.
BREVETTI INDUSTRIALI: "Uso degli antagonisti della Sostanza P nel trattamento
degli adenocarcinomi dell'apparato uro-genitale, depositato nel 1999, internazionalizzato
nel 2001.
SOCIETA' DI APPARTENENZA:
- SIAS (Societa' Italiana Alimentazione e Sport)
- New York Academy of Sciences.
- SSIB (Societa' internazionale per gli studi sull'"ingestive behaviour").
- Society for Neuroscience.
- IBRO. - Societa' italiana di Farmacologia.
- Health and Fitness Association.
CURRICULUM PROFESSIONALE
Dal 1987 e' stato studente interno presso l'Istituto di Farmacologia dell'Universita'
degli studi di Camerino, dove ha effettuato la tesi sperimentale di laurea.
Dal 1987 al 1991 ha collaborato con il Prof. de Caro ed il Prof. Massi su studi
relativi all'" ingestive behaviour" con particolare riguardo a ricerche riguardanti
i meccanismi centrali coinvolti nell'assunzione di acqua, nell'appetito per il
sodio e nell'assunzione di alcool. Ha, inoltre, effettuato studi sul sistema cardiovascolare
di ratto con l'impiego di modelli di ratti anestetizzati e "freely moving".
Dal 1989 al 1990 ha tenuto i corsi di Esercitazione pratiche di laboratorio di
Farmacologia agli studenti del corso di Farmacia.
Dal 1991 al 1994 ha lavorato presso il laboratorio di Neuroendocrinologia dell'Universita'
Rockefeller di New York, USA, Dr. Bruce McEwen, nel campo della biologia molecolare
con particolare riguardo all'applicazione delle metodologie di "ibridizzazione
in situ" e "binding" recettoriali allo studio delle alterazioni dei livelli di
RNA messaggero di peptidi cerebrali coinvolti nell'omeostasi dei fluidi corporei.
Dal 1993 al 1994 ha tenuto il corso di Human Anatomy and Physiology presso "
Hostos Community College" di New York, USA, in qualita' di "Adjunct Assistant
Professor".
1995: vincitore del concorso per Ricercatore, settore disciplinare EO7X, presso
il Dipartimento di Scienze Farmacologiche e Medicina Sperimentale dell'Universita'
degli studi di Camerino.
Da Luglio 1995 a Gennaio 1996 "Visiting Assistant Professor" presso il laboratorio
di Neuroendocrinologia dell'Universita' Rockefeller di New York, USA.
Da Agosto 1996 a Ottobre 1996 "Visiting Assistant Professor" presso il laboratorio
di Neuroendocrinologia dell'Universita' Rockefeller di New York, USA.
1998: Ricercatore confermato, settore disciplinare EO7X, presso il Dipartimento
di Scienze Farmacologiche e Medicina Sperimentale dell'Universita' degli studi
di Camerino.
1999: Incarico di docenza degli insegnamenti di Farmacologia Molecolare e Neuropsicofarmacologia
presso la facolta' di Farmacia dell'Universita' di Camerino.
1999 Docente del corso di Istruttore di Body Building di I livello per la Federazione
Italiana Nabba (Federazione di Body Building).
Conferimento presso la Facolta' di Farmacia dei seguenti insegnamenti:
- Affidamento di "Farmacologia Molecolare"
- corso di laurea in Chimica e Tecnologia Farmaceutiche
- A.A. 1998/99-1999/2000-2000/2001; - Affidamento di " Neuropsicofarmacologia"
- corso di laurea in Chimica e Tecnologia Farmaceutiche
- A.A. 1999/2000; - Affidamento di " Farmacologia e Farmacoterapia II"
- Io mod. Chemioterapia Antimicrobica ed Antitumorale
- corso di laurea in Farmacia - A.A. 200/2001;
- Affidamento di "Chemioterapia Antimicrobica ed Antitumorale"
- Io mod. Didattico di 5 CFU dell'insegnamento di Farmacologia e Farmacoterapia
II, 4o anno
- corso di laurea Specialistica in Farmacia
- A.A. 2001/2002; - Affidamento di "Biotecnologie Farmacologiche "
- insegnamento di 4 CFU - corso di laurea Specialistica in Chimica e Tecnologia
Farmaceutiche
- A.A. 2001/2002; - Affidamento di "Farmacoeconomia"
- 1CFU - corso di laurea in Informazione Scientifica sul Farmaco
- A.A. 2001-2002-2003;
- Carico didattico di "Farmacologia e Farmacoterapia II"
- IIo mod. Chemioterapici Antimicrobici e Antitumorali 5CFU
- corso di laurea Specialistica in Farmacia - A.A. 2002/2003 a tutt'oggi;
- Carico didattico di "Farmacologia" 4CFU
- corso di laurea Specialistica in Chimica e Tecnologia Farmaceutiche
- A.A. 2002/2003 a tutt'oggi;
- Carico didattico di "Biotecnologie Farmacologiche "
- insegnamento di 4 CFU
- corso di laurea Specialistica in Chimica e Tecnologia Farmaceutiche
- A.A. 2002/2003 a tutt'oggi;
- Carico didattico di "Farmacologia Molecolare n.o."
- corso di laurea Specialistica in Chimica e Tecnologia Farmaceutiche
- A.A. 2002/2003 a tutt'oggi;
- Carico didattico di "Farmacologia e Farmacoterapia II"
- IIo mod. Chemioterapici Antimicrobici e Antitumorali 5CFU
- corso di laurea in Informazione Scientifica sul Farmaco
- A.A. 2002/2003 a tutt'oggi;
- Carico didattico di "Farmacologia", 6+2 CFU
- corso di Laurea in Biotecnologie
- A.A. 2002/2003 a tutt'oggi.
2002: Docente del corso di: "Impiego dei nutraceutici nell'attivita' agonistico-sportiva"
per l'Educazione Continua in Medicina dei Farmacisti presso l'Ordine professionale
dei Farmacisti della provincia di Macerata ed Ascoli Piceno.
Attivita' seminariale su: "Impiego dei nutraceutici nell'attivita' agonistico-sportiva:
dubbi e certezze" presso l'Associazione Sportiva Ascoli Calcio. - 2003: Organizzatore
e Direttore del Master Universitario di I livello in: Scienze dello Sport e del
Fitness: aspetti Fisiologici, Nutrizionali e Farmacologici. - 2003: Presidente
Regionale Marche SIAS (Societa' Italiana Alimentazione e Sport). - 2003: Idoneita'
di giudizio a Professore Associato di Farmacologia e Farmacoterapia Dal 1997 ad
oggi: Responsabile del laboratorio di Biotecnologie Farmacologiche presso il Dipartimento
di Scienze Farmacologiche e Medicina Sperimentale dell'Universita' degli studi
di Camerino, coinvolto nei seguenti argomenti di ricerca:
1) Neurokinine ed angiogenesi nello sviluppo degli adenocarcinomi nell'apparato
uro-genitale.
2) Espressione genica di neuropeptidi nelle patologie cardiovascolari.
3) Alterazioni dell'espressione genica di neuropeptidi nella malattia di Alzheimer.
4) Coinvolgimento ed espressione genica di neuropeptidi nell'invecchiamento.
5) Modificazioni dell'espressione genica delle neurokinine indotte da assunzione
di sostanze d'abuso.
TECNICHE:
- Chirurgia stereotassica e posizionamento di cannule intracerebroventricolari
- Chirurgia generale su piccoli animali
- Tecniche istochimiche e citochimiche
- Autoradiografia
- Neuroanatomia
- Colture cellulari
- Analisi d'immagine.
PUBBLICAZIONI
Pompei, P., Polidori, C., Perfumi, and Massi, M. Sensitivity of Spontaneously
Hypertensive and of Wistar Kyoto rats to the antidipsogenic effect of Eledoisin.
Reg. Peptides, 28, 119-129, 1990, (Amsterdam, The Netherlands).
Polidori, C., Pompei, P., Perfumi, M., Melchiorre, C. and Massi, M.. Natriuresis,
kaliuresis and antidiuresis induced by central carbachol injection are mediated
by M1 muscarinic receptors. Europ. J. Pharmacol., 195, 139-143, 1991, (Amsterdam,
The Netherlands).
Perfumi, M., Polidori, C., Pompei, P., de Caro, G., and Massi, M. The tachykinin
NH2 Senktide selectively inhibits alcohol intake in alcohol-preferring rats. Pharmacol.
Biochem. Behav., 38, 881-887, 1991, (Tarrytown, NY, USA).
Pompei, P., Tayebaty, J., de Caro, G., Schulkin, J. and Massi, M .. Bed nucleus
of the stria terminalis: site for the antinatriorexigenic action of tachykinins
in the rat. Pharmacol. Biochem. Behav., 40, 977-981, 1991, (Tarrytown, NY, USA).
Achapu, M., Pompei, P., Massi, M. and de Caro, G.. Central effects of Neuropeptide
K on the rat ingestive behaviour. Brain Res. Bullettin, 28, 299-303, 1992, (Tarrytown,
NY, USA).
Massi, M., Gentili, L., Pompei, P., de Caro, G. and Epstein, A.. Central tachykinin
injection potently suppresses the need-free salt intake of the female rat. Brain
Res. 584, 77-82, 1992, (Amsterdam, The Netherlands).
Polidori, C., Panocka, I., Perfumi, M., Pompei, P., de Caro, G. Massi, M.. Inhibition
of cell-dehydration-induced drinking by tachykinins: evaluation of possible renal
effects accounting for the long lasting inhibition. Physiol. Behav. 52, 153-158,
1992, (Tarrytown, NY, USA).
Pompei, P., Tayebaty, J., Massi, M. and de Caro, G.. Hypotensive effects of intravenous
injection of tachykinins in conscious freely moving Spontaneously Hypertensive
and Wistar Kyoto rats. Peptides, 14, 97-102, 1993, (Tarrytown, NY, USA).
Panocka, I., Pompei, P., and Massi, M. Suppression of alcohol preference in rats
following risperidone, a serotonin 5-HT2 and dopamine D2 receptor antagonist.
Brain Res. Bull., 31, 595-599, 1993, (Tarrytown, NY, USA).
Giardina', D., Gulini, U., Massi, M., Piloni, M.G., Pompei, P., Rafaiani, G.,
Melchiorre, C. Structure-activity relationships in prazosin-related compounds
2. Role of the Piperazine Ring on ?-Blocking Activity. J. Med. Chem., 36, 690-698,
1993, (NY, USA).
Pompei, P., Magarinos, A.M., Angulo, J. and McEwen, B. In situ hybridization
analysis of preprotachykinin mRNA levels in discrete areas of the rat brain: an
involvement of tachykinins in different natriorexigenic treatments. In: Cellular
Communication in reproduction. (Eds. Facchinetti, Henderson, Pierantoni and Polzonetti-Magni),
J. Endocrinol., (Bristol, U.K.) pp.49-54, 1993.
Panocka, I., Ciccocioppo, R., Pompei, P., Massi, M.. 5HT-2 receptor antagonists
do not reduce alcohol intake in Sardinian alcohol preferring (sP) rats. Pharmacol.
Biochem. Behav., 46 (1993) 853-856.
Ciccocioppo, R., Panocka, I., Pompei, P., de Caro, G. and Massi, M.. Selective
agonists at NK-3 tachykinin receptors inhibit alcohol intake in Sardinian alcohol-preferring
rats. Brain Res. Bullettin, 33 (1) 71-77, 1994 (Tarrytown, NY, USA).
Ciccocioppo, R., Polidori, C., Pompei, P., de Caro, G. and Massi, M. Inhibition
of isotonic chloride intake in the rat by selective tachykinin agonists. Physiol.
Behav., 52 (1) 153-158, 1994 (Tarrytown, NY, USA).
Panocka, I., Ciccocioppo, R., Polidori, C., Pompei, P., and Massi M. The 5-HT4
receptor antagonist, GR 113808, reduces ethanol intake in alcohol-preferring rats.
Pharmacol. Biochem.Behav., 52 (2) 255-259, 1995.
Ciccocioppo, R., Panocka, I., Pompei, P., Polidori, C., de Caro, G. and Massi,
M. Subcutaneous injections of the tachykinin Senktide reduce alcohol intake in
alcohol-preferring rats. Peptides, 16 (3) (1995) 533-537.
Riftina, F., Angulo, J., Pompei, P. and McEwen, B.S. Regulation of Angiotensinogen
gene expression in the rat forebrain by adrenal steroids and relation to salt
appetite. Mol. Brain Res. 33 (1995) 201-208.
Pompei, P., Riftina, F., and McEwen, B. Effect of adrenal steroids on Preprotachykinin-A
gene expression in discrete regions of the rat brain. Mol. Brain Res., 33 (1995)
209-216.
Polidori, C., Ciccocioppo, R., Pompei, P., Cirillo, R., Massi, M. The selective
angiotensin AT1 receptor antagonist LR-B/081 potently inhibits drinking induced
by central injection of angiotensin II in rats. Eur. J. Pharmacol. 227 (1995)
223-228.
Polidori, C., Ciccocioppo, R., Pompei,P., Cirillo, R., and Massi, M., Functional
evidence of angiotensin AT1 receptor antagonists to cross the blood- brain barrier
in rats. Eur. J. Pharmacol. 307 (1996) 259-267.
Polidori, C., Pompei, P., Ciccocioppo, R., de Caro, Massi, M. Effects of the
selective tachykinin NK-3 receptor agonist NH-2-senktide on intraoral intake and
taste reactivity responses elicited by NaCl in sodium-replete rats. Reg. Peptides,
66, 101-104, 1996.
Giardina', D., Crucianelli, M., Marucci, G., Melchiorre, C., Polidori, C., Pompei,
P., Massi, M. Pharmacological evaluation of prazosin- and doxazosin-related compounds
with modified piperazine ring. Arzneim.-Forsh./Drug. Res. 46 (II) (1996) 1054-1059.
Pompei, P., Angeletti, S., Polidori, C., Ciccocioppo, R., de Caro, G., Massi,
M. Regulation of preprotachykinin-A messenger RNA in genetic hypertensive and
normotensive rats. Mol. Brain Res., 47 (1997) 78-86.
Lucas, L.R., Pompei, P., McEwen, B.S., Effects of deoxycorticosterone acetate
and diazepam on neuropeptidergic neurons in rat striatum. Neurorep. 8 (1997) 811-816.
Pompei, P., Lucas, L., Angeletti, S., Massi, M., McEwen, B.S. In situ hybridization
analysis of Preprotachykinin-A and B mRNA levels in short-term sodium depletion.
Mol. Brain Res., 49 (1997) 149-156.
Lucas, L.R., Pompei, P., Ono, J., and B.S. McEwen. Effects of adrenal steroids
on basal ganglia neuropeptide-mRNA and tyrosine hydroxylase radioimmunoreactive
levels in the adrenalectomized rat. J. Neurochem., 71 (1998) 833-843.
Pompei, P., Angeletti, S., Ciccocioppo, R., Colombo, G., Gessa, G.L., Massi,
M. Preprotachykinin-A gene expression in the forebrain of sardinian alcohol-preferring
and-non preferring rats, Mol. Brain Res., 56/1-2 (1998) 277-280.
Pompei P., Severini, R., G. Costa, M. Massi, P. Fattoretti, and C. Bertoni-Freddari.
In situ hybridization analysis of preprotachykinin-A mRNA levels in young and
old rats, Mol. Brain Res., 64 (1): (1999) 132-136.
Lucas, L.R., Pompei, P., McEwen, B.S., Correlates of deoxycorticosterone-induced
salt appetite behavior and basal ganglia neurochemistry. Ann. N.Y. Acad. Sci.,
897: 423-8, 1999.
Santoni, G., Perfumi, M.C., Pompei, P., Spreghini, E., Lucciarini, R., Martarelli,
D., Staffolani, M. and Piccoli, M. Impairment of rat thymocyte differentiation
and functions by neonatal capsaicin treatment is associated with induction of
apoptosis J. Neuroimmunol. 3; 104 (2000) (1):37-46.
Lucas, R.L., Pompei, P., McEwen, B.S., Salt appetite in salt replete rats: involvement
of mesolimbic structures in deoxycorticosterone-induced salt-craving behaviour.
Neuroendocrinol., 71 (2000) (6): 386-395.
Pompei, P., Severini, R., Pediconi, D., Angeletti, M., Eleuteri, A., Fattoretti,
P., Bertoni-Freddari, C., Fioretti, E., Regulation of Preprotachykinin-A mRNA
gene expression in an animal model of Alzheimer's disease. J. Histochem. Cytochem.,
49, 1-2, 2001.
P. Pompei , R. Severini , D. Pediconi , D. Martarelli , M. Massi , P. Fattoretti
, C. Bertoni-. In situ hybridization analysis of preprotachykinin-A mRNA levels
in young and old rats. J. Histochem. Cytochem., vol 49:1-2 2001.
Fattoretti, P., Bertoni-Freddari, C., Di Stefano, G., Casoli, T., Gracciotti,
N., Solazzi, M., Pompei, P., Quantitative immunohistochemistry of glucose transport
protein (Glut 3) expression in the rat hippocampus during aging, J. Histochem.
Cytochem., vol 49:1-2 2001.
Fattoretti, P., Bertoni-Freddari, C., Di Stefano, G., Casoli, T., Gracciotti,
N., Solazzi, M., Pompei, P., Mapping of mitochondrial metabolic competence by
cytochrome oxidase and succinic dehydrogenase cytochemistry, J. Histochem. Cytochem.,
vol 49 (5):1-2 2001.
Santoni, G., Amantini, C., Lucciarini, R., Pompei, P., Perfumi, M., Nabissi,
M., Morrone, S., Piccoli, M., Expression of Substance P and its Neurokinin type-1
receptor on thymocytes: functional relevance in the regulation of thymocyte apoptosis
and proliferation, Neuroimmunol., vol. 376, 232-246, 2002.
Pompei, P., Cavazzuti, E., Martarelli, D., Pediconi, D., Arletti, R., Lucas,
L.R., and Massi, M. Preprotachykinin-A mRNA gene expression after administration
of 3,4 methylendioxymetamphetamine (Ecstasy), Eur. J. Pharmacol., 450 (3): 245,
2002.
Ciccocioppo, R., Antonelli, L., Biondini, M., Perfumi, M., Pompei, P., and Massi.
M., Memory impairment following combined exposure to ?9-tetrahydrocannabinol and
ethanol in rats, Eur. J. Pharmacol., 449: 245-252, 2002.
Santoni, G., Amantini, C., Lucciarini, R., Perfumi, M.C., Pompei, P., and Piccoli,
M.. Neonatal capsaicin treatment affects rat thymocyte proliferation and cell
death by modulating substance P and neurokinin-1 receptor expression, Neuroimmmunomod.,
414, in press, 2003.
D. Martarelli, B. Martarelli, D. Pediconi, M. I. Nabissi, M. Perfumi, P. Pompei.
Hypericum Perforatum Methanolic Extract Inhibits Growth of Human Prostatic Carcinoma
Cell Line Orthotopically Implanted in Nude Mice. In Press (Cancer Letters)
CONFERENZE ED ABSTRACTS
Pompei, P., Massi, M., de Caro, G. and Perfumi, M.. Sensitivity of Spontaneously
Hypertensive and of Wistar Kyoto rats to the antidipsogenic action of Eledosin.
Xth International Conference on the " Physiology of food and fluid intake", Paris,
July, 4-8, Appetite, 12, 231, 1989.
Pompei, P., Massi, M., de Caro, G., and Perfumi, M.. Cenral effects of Eledoisin
on drinking behaviour of Spontaneously Hypertensive and of Wistar Kyoto rats .
International workshop on sensory neuropeptides, Florence, June 1-2, 1989.
Pompei, P., Massi, M., Perfumi, M and de Caro, G., Spontaneously Hypertensive
rats are less sensitive than Wistar Kyoto rats to the antidipsogenic action of
Eledosin. Quarta riunione Societa' Italiana di Farmacologia, gruppo Interregionale
, Bologna 15 Dicembre1989.
Massi, M., Perfumi, M., Pompei, P., Polidori, C, and de Caro, G.. Inhibition
of ethanol intake in the rat by central injection of the tachykinin NH2. Functional
and Pharmacological aspects of neuropeptides: a national meeting, Florence, June
22, 1990.
Massi, M., Perfumi, P., Polidori, C. M., Pompei, and de Caro. G.. Inhibition
of ethanol intake in the rat by central injection of the tachykinin NH2. XI International
Congress of Pharmacology, Amsterdam, July 2-6, 1990. Eur. J. Pharmacol. 183, 488,
1990.
De Caro, G., Perfumi, M., Polidori, C., Pompei, P and Massi, M.. Effects of central
injection of tachykinins on alcohol intake in rats. XXV national meeting of the
italian Society of Pharmacology, Taormina, Giardini Naxos, October 14-18, 1990.
De Caro, G., Perfumi, M., Polidori, C., Pompei, P and Massi, M.. Effects of central
injection of tachykinins on alcohol intake in rats. XXV national meeting of the
italian Society of Pharmacology, Taormina, Giardini Naxos, October 14-18, 1990.
Pharmacol. Res., 22 (suppl. 2), 154, 1990.
Pompei, P., Massi, M., . and Perfumi, M., de Caro, G., Spontaneously Hypertensive
rats are less sensitive than Wistar Kyoto rats the antidipsogenic action of Eledoisin.
4th meeting of the italian Society of Pharmacology, Bologna, December 15th, 1989.
Pharmacol. Res., 22 (suppl.1), 127-128, 1990.
Pompei, P., Tayebaty, J., Massi, M., de Caro, G., Peripheral cardiovascular effects
of tachykinins in conscious freely moving Spontaneously Hypertensive and Wistar
Kyoto rats. Sensory neuropeptides: Physiopathological and Pharmacological aspects,
Camerino, May 24, 1991.
Pompei, P., Tayebaty, J., de Caro, G. and Massi, M.. Bed nucleus of the stria
terminalis: site for the antinatriorexic action of tachykinins in the rat. Sensory
neuropeptides: Physiopathological and Pharmacological aspects, Camerino, May 24,
1991.
Pompei, P., Tayebaty, J., Massi, M.and de Caro, G. Peripheral cardiovascular
effects of tachykinins in conscious freely moving Spontaneously Hypertensive and
Wistar Kyoto rats. 6th Meeting Inter-regionale della Societa' italiana di Farmacologia,
Ancona, 23 Aprile, 1991.
Pompei, P., Tayebaty, J., Massi, M.and de Caro, G. Peripheral cardiovascular
effects of tachykinins in conscious freely moving Spontaneously Hypertensive and
Wistar Kyoto rats. 6th Meeting Inter-regionale della Societa' italiana di Farmacologia,
Ancona, 23 Aprile, 1991. Pharmacol. Res., 25 (suppl.. 1), 67, 1991.
Pompei, P., Tayebaty, S.J., Perfumi, M., de Caro, G. and Massi, M. Sensitivity
of the bed nucleus of the stria terminalis to the antinatriorexigenic action of
tachykinins. Third IBRO World Congress of Neuroscience, Montreal (Canada), 4-9
August, 1991, p. 150.
Massi, M., Pompei, P., Gentili, L., de Caro, G., Epstein, A.N. Central injection
of tachykinins potently suppresses the need-free salt intake of female rats. Third
IBRO World Congress of Neuroscience, Montreal (Canada), August 4-9, 1991, p. 150.
Ciccocioppo, R., Pompei, P., Polidori, C., Massi, M. and de Caro, G. Inhibitory
effect of the NK-3 selective agonist NH2-Senktide on the need-free salt intake
of the rat. 2nd Meeting of the European Neuropeptide Club. Pisa, May 14-16th,
Neuropeptides, 22, 14, 1992.
Tayebaty, S.J., Orlando, C., Pompei, P., de Caro, G. and Massi, M. NK-1 and NK-3
tachykinin receptors in the bed nucleus of the stria terminalis mediate salt appetite
inhibition in rats. 2nd Meeting of the European Neuropeptide Club. Pisa, May 14th-16th,
Neuropeptides, 22, 65, 1992.
Pompei, P., Tayebaty, J., de Caro, G. and Massi, M.. Bed nucleus of the stria
terminalis: site for the antinatriorexigenis action of tachykinins in the rat.
First independent SSIB Conference, Princeton, NJ, USA, June 24-28, 1992.
Pompei, P., Magarinos A.M., Angulo, J. and McEwen, B.. In situ hybridization
analysis of Preprotachykinin mRNAs in discrete regions of the rat brain: an involvement
of tachykinins in different natriorexigenic treatments. 22nd Annual Meeting of
the Society for Neuroscience, Anaheim, CA, USA, October 25-30, 1992.
Polidori, C., Pompei, P., Massi, M., Epstein, A.N. and Sakai, R.R, Inhibition
of sodium appetite by oxytocin in female but not in male rats. 22nd Annual Meeting
of the Society for Neuroscience, Anaheim, CA, USA, October 25-30, 1992.
Panocka, I., Pompei, P., and Massi, M. Suppression of ethanol preference in
rats by 5HT2 receptors antagonists. 5th Meeting of the italian Society for Neuroscience.
Modena, 1-4 Dicembre, 1992. Neurosci. Lett., suppl. 43, 1992, S81.
Ciccocioppo, R., Panocka, I., Pompei, P., and Massi, M. Central 5HT2 receptors
may control ethanol intake in the rat. 11th International Conference on the Physiology
of Food and Fluid intake. Oxford, 28-30 July 1993.
Riftina, F., Pompei, P., McEwen, B., Sodium depletion decreases the level of
vasopressin mRNA in the supraoptic nucleus of the rat. 11th International Conference
on the Physiology of Food and Fluid intake. Oxford, 28-30 July 1993.
Pompei, P., Riftina, F., McEwen, B. Preprotachykinin-A mRNA expression in discrete
brain regions: an in situ hybridization study. 11th International Conference on
the Physiology of Food and Fluid intake. Oxford, 28-30 July 1993.
Pompei, P., Riftina, F., McEwen, B. Effects of desoxycorticosterone acetate administration
on Preprotachykinin-A mRNA gene expression in discrete rat brain region: an in
situ hybridization analysis. 23rd Annual Meeting of the Society for Neuroscience,
Washington, November 7-12, 1993.
Riftina, F., Pompei, P., Angulo, J., Canbeily, R., McEwen, B. Effects of an extended
sodium depletion on the expression of vasopressin and angiotensinogen mRNAs in
the rat brain. 23rd Annual Meeting of the Society for Neuroscience, Washington,
November 7-12, 1993.
Massi, M., Ciccocioppo, R., de Caro, G., Polidori, C., Pompei, P., Tachikinine
ed assunzione edonica di sale, MURST, Firenze 30 Maggio 1994.
Ciccocioppo, R., Panocka, Pompei, P., Polidori, C. and Massi, M. Behavioural
evidence of different regulation of the 5HT-2 receptor mechanisms in Sardinian
alcohol-preferring rats. Joint Meeting: 10-13 July 1994, Cambridge, UK. J. Psycopharmacol.
Massi, M., Panocka, I., Ciccocioppo, R., Polidori, C., Pompei, P., 5-HT2 antagonists
and alcohol intake in rats: lights and shadows, Fifth meeting of the European
Behavioural Pharmacology Society. Berlin, Germany, 11-15 September 1994 Behav.
Pharmacol., 5: 98; 1994.
Polidori, C., Ciccocioppo, R., Pompei, P., Panocka. I., Massi, M., The angiotensin
AT1 receptor antagonist LR-B/081 is a potent and selective inhibitor of angiotensin
II-induced drinking in rats. XXVII Congresso nazionale SIF, Torino, 25-29 Settembre,
1994.
Massi, M., Polidori, C., Ciccocioppo, R., Pompei, P., Panocka. I. Suppression
ethanol intake in rats by the 5-HT2 receptor antagonist ritanserin: possible site
and mechanism of action. XXVII Congresso nazionale SIF, Torino, 25-29 Settembre,
1994.
Panocka, I., Polidori, C., Ciccocioppo, R., Pompei, P., and Massi, M. Suppression
ethanol preference in rats induced by risperidone, a 5-HT2 and dopamine D2 receptor
antagonist. XXVII Congresso nazionale SIF, Torino, 25-29 Settembre, 1994.
Massi, M. ., Ciccocioppo, R., Pompei, P., Panocka. I. Why do 5-HT2 antagonist
not reduce alcohol intake in Sardinian alcohol-preferring (sP) rats genetically
selected for high ethanol intake. The International Workshop of Emotional and
Motivational Mechanism of Behaviour: Neurobiological, Pharmacological and Psychological
Aspects. Warsaw, Polan, October 13-15, 1994.
Massi, M. Panocka. I., Polidori, C., Ciccocioppo, R., Pompei, P. Further evidence
that 5-HT4 receptor antagonist uppress alcohol intake in rats. First European
Congress of Pharmacology. Milan Italy, June 16-19, 1995.
Massi, M. ., Ciccocioppo, R., de Caro, G., Polidori, C., Pompei, P. Possible
mechanism for the antinatriorexic action of tachykinin NK3 receptor agonist in
rats. Tachykinin '95. Florence, Italy, October 16-18, 1995.
Polidori, C., de Caro, G., Perfumi M., Ciccocioppo, R., Pompei, P. Massi, M.
Tachykinin receptors mediating the effects of neuropeptide gamma on vater intake
in rats. Tachykinin '95. Florence, Italy, October 16-18, 1995.
Polidori, C., Pompei, P., Ciccocioppo, R., de Caro, G. and Massi. M. Reattivita'
gustativa e tests di assunzione orale nello studio dell'azione antinatriorexica
delle tachikinine. Metodi Innovativi in Farmacologia. Firenze, 20-21 Ottobre 1995.
Pompei, P., Polidori, C., Ciccocioppo, de Caro, G. and Massi. Espressione genica
della preprotachikinina A in aree cerebrali di ratti spontaneamente ipertesi e
di ratti Wistar Kioto. Metodi Innovativi in Farmacologia. Firenze, 20-21 Ottobre
1995.
Pompei, P., McEwen, B.S., Polidori, C., de Caro, G., and Massi, M. Regulation
of preprotachykinin-A gene expression and relation to sodium appetite. 3rd Joint
Meeting of the italian and french societies of Pharmacology, Capri, 23-26 May
1996, Fund. Clin. Pharmacol. 10, n.2, p. 210.
Massi, M., Pompei, P., Angeletti, S., Polidori, C., Ciccocioppo, R., de Caro,
G. In situ hybridization analysis of Preprotachikinin A (PPT-A) mRNA in Spontaneously
Hypertensive and Wistar rats. VI Symphagium Benjiamin Franklin-Lafayette. La Napoule,
France, 2-8 june, 1996.
Polidori, C., Pompei, P., Ciccocioppo, R., de Caro, G. and Massi, M. Central
NK-3 receptors: a role in taste mechanisms. European Neuropeptide Club, 6th annual
meeting, 16-19 June 1996, Pecs, Hungary. Neurobiol., 4, 1996 p. 166.
Pompei, P., Angeletti, S., Polidori, C., Ciccocioppo, R., de Caro, G., Massi,
M. Regulation of preprotachykinin-A messenger RNA in genetic hypertensive and
normotensive rats. European Neuropeptide Club, 6th annual meeting, 16-19 June
1996, Pecs, Hungary. Neurobiol., 4, 1996 p. 166.
Polidori, C., Pompei, P., Ciccocioppo, R., de Caro, G. and Massi, M. Brain Tachynins:
a role in taste mechanisms. 5th Joint Meeting of Hungarian, Italian and Polish
Pharmacological Societies. Pecs, Hungary, 20-22 june 1996.
Pompei, P., Angeletti, S., de Caro, G., Massi, M., McEwen B.S. Regulation of
preprotachykinin-A and preprotachykinin-B mRNA in the rat brain in response to
sodium depletion. XXVIII National Congress of the Italian Pharmacological Society.
Bari, Italy, April 30-May 3, 1997 Pharmacol. Res., 35, suppl. p. 13.
Pompei, P., Angeletti, S., Ciccocioppo, R., Colombo, G., Gessa, G., Massi, M.
Preprotachynin-A gene expression in the brain of Sardinian alcohol-preferring
(sP) and -nonpreferring (sNP) rats. 7th Annual Meeting of the European Neuropeptide
Club. Marburg, Germany, May 21-24, 1997.
Pompei, P., Angeletti, S., Ciccocioppo, R., Colombo, G., Gessa, G., Massi, M.
Preprotachynin-A gene expression in the brain of Sardinian alcohol-preferring
(sP) and -nonpreferring (sNP) rats. 6th Congress of the European Society for Biomedical
Research on Alcoholism. Stockholm, Sweden, June 28-July 1; 1997. Alcohol Alcohol.:
32; 378; 1997.
Ciccocioppo, R., Panocka, I., Polidori, C., Pompei, P., Massi, M. Conditioned
place preference after intragastric ethanol administration in alcohol-preferring
rats. 6th Congress of the European Society for Biomedical Research on Alcoholism.
Stockholm, Sweden, June 28-July 1; 1997. Alcohol Alcohol.: 32; 378; 1997.
Pompei, P., Angeletti, S., Polidori, C., Ciccocioppo, R., de Caro, G and Massi,
M. Regulation of preprotachykinin-A mRNA in genetic hypertensive and normotensive
rats. International tachykinin conference: tachykinins in health and disease.
7-11 September 1997, Cairns, Great Barrier Reef, Australia.
Pompei, P., Massi, M., Ciccocioppo, R., Panocka, I., de Caro, G. Sensitivity
of brain sites to the inhibitory effect on alcohol intake by tachykinin agonists.
International tachykinin conference: tachykinins in health and disease. 7-11 September
1997, Cairns, Great Barrier Reef, Australia.
Pompei, P., Lucas, L.R. Angeletti, S., Massi M., and McEwen, B.S. In situ hybridization
analysis of preprotachykinin-A and B mRNAs in short-term sodium depletion. 27th
Annual meeting of the Society for Neuroscience, New Orleans, 25-30 October 1997.
Lucas, L.R., Pompei, P., and McEwen, B.S., Effects of Deoxycorticosterone acetate
and Diazepam on neuropeptidergic neurons in rat striatum. 27th Annual meeting
of the Society for Neuroscience, New Orleans, 25-30 October 1997.
Lucas, L.R., Pompei, P., and McEwen, B.S., Correlates of deoxycortecosterone-induced
salt appetite behaviour and basal ganglia neurochemistry. 28th Annual meeting
of the Society for Neuroscience, Los Angeles, November 7-12 1998.
Polidori, C., Calo', G., de Caro, G., Regoli, D., Pompei, P., Massi, M., Sensitivity
of brain sites to the orexigenic effect of nociceptin (NC) or of its analog [Phe1y
(CH2-NH)Gly2] NC (1-13) NH2. 9th Meeting of the European Neuropeptide Club, Ferrara,
Italy, May 12-15, 1999.
Pompei, P., Cavazzuti, E., Martarelli, D., Lucciarini, R., Arletti, R. and Massi,
M., Preprotachykinin-A gene expression and behavioural correlates after administration
of MDMA (ecstasy), Pharmacol. Res., XXIX National Congress of the Italian Pharmacological
Society, Florence, Italy, June 20-23, 1999.
Pompei, P., Cavazzuti, E., Martarelli, D., Lucciarini, R., Arletti, R., Massi,
M. Analisi di ibridizzazione in situ della preprotachikinina-A e correlati comportamentali
dopo somministrazione di MDMA (Ecstasy), CNB3 3o Congresso Nazionale Biotecnologie,
Urbino, 1-3 Luglio 1999.
Santoni, G., Perfumi, M., Pompei, P., Lucciarini, R., Staffolani, M., Spreghini,
E., Martarelli, D., Piccoli, M. In vivo Substance P administration reverses capsaicin-induced
apoptosis of thymus cell subpopulations. The fourth international congress, International
Society for Neuroimmunomodulation. ISNIM-99, Lugano, Switzerland, September 29-October
02, 1999.
Lucas, L.R., Pompei, P., McEwen, B.S., Short-term sodium depletion: interaction
of brain dopaminergic and peptidergic systems in salt seeking behavior, 29th Annual
Meeting, Society for Neuroscience, Miami Beach, FA, USA October 23-28, 1999.
Pompei, Severini, R., Pediconi, D., Angeletti, M., Eleuteri, A., Marchini, C.,
Fioretti, E., Regulation of substance P gene expression in an animal model of
Alzheimer disease. Genetics in Neuroscience, Acts of 2nd International Congress,
Terni (Italy), 2-5 July, 2000.
Pompei, P., Cavazzuti, E., Martarelli, D., Arletti, R., Lucas, L. R., Massi,
M., Regulation of Preprotachykinin-A gene expression and behavioural correlates
after administration of 3,4- methylendioxymetamphetamine (ecstasy). International
Tachykinin conference, Tachykinins 2000, La Grande Motte, France, October 17-20,
2000.
Pompei, P., Panocka, I., Ciccocioppo, R., Angeletti, S., Massi, M., The Psychopharmacology
of tachykinin NK-3 receptors in laboratory animals. International Tachykinin conference,
Tachykinins 2000, La Grande Motte, France, October 17-20, 2000.
Santoni, G., Pompei, P., Perfumi, M., Nabissi, M., Spreghini, E., Lucciarini,
R., Amantini, C., Martarelli, D., Martarelli, B., Morrone, S., Piccoli, M. Expression
of NK-1 receptor in rat thymocyte. Role of substance P/NK-1 receptor autocrine
pathway on rat thymopoiesis. International Tachykinin conference, Tachykinins
2000, La Grande Motte, France, October 17-20, 2000.
Ciccocioppo, R., Pompei, P., Massi, M., Reduction of ethanol self-administration
by the "antiopioid" peptide nociceptive/orphanin FQ. 30th Annual Meeting, Society
for Neuroscience, San Diego, Ca.
Pompei, P., Severini, R., Martarelli, D., Pediconi, D., Angeletti, M., Fioretti,
E., Massi, M., Regulation of preprotachykinin-A gene expression in an animal model
of Alzheimer disease. XXX congresso Nazionale SIF, Genova 30 Maggio, 2 Giugno,
2001, Pharmacol Res., vol. 48, suppl. A
Pompei, P., Martarelli, D., Pediconi, D., Sala, E., Arletti, R., Massi, M. Preprotachykinin-A
gene expression after subchcronic administration of morphine. XXX congresso Nazionale
SIF, Genova 30 Maggio, 2 Giugno, 2001, Pharmacol Res., vol. 48, suppl. A
Pompei, Martarelli, B., Martarelli, D., Pediconi, D., Nabissi, M.I. Involvement
of Neurokinin-1 receptor in prostate cancer cancer development. International
conference: Molecular mechanisms as targets in prostatic diseases, Liverpool UK
17-20 September 2002.
Pompei, Martarelli, B., Martarelli, D., Pediconi, D., Nabissi, M.I. Involvement
of Neurokinin-1 receptor in prostate cancer cancer development. 31o National Congress
of the Italian Society of Pharmacology, Trieste, Italy, 26-29th June, 2003.